Meh I got tires on my bike rated to 71mph. Tires rated for 100mph+ are available.
Frame? Speed is not what is unsafe. Impacts are, at speed. A smooth drag strip does not " impact load" the frame. Impact loadign at 25mph ( jumps, bumps) is very well more stress on the frame than riding along a flat track at 125mph+. Certainly. Yes, "impact loadign " plus "very high speed" is not good, and is worse. However, a racetrack or drag strip are designed smooth, with banks, and do not impact load frames ( unless you are in a crash).
You would certainty want a high end suspension. Purpose built... for " smooth" and " fast". Pay careful attention to the rakes, and the ground trail, spring rates, wheelbase. A steering damper might also be a good idea with this level of force on the steering head. If you begin to have a floppy oscillation of the front end. Flop is easy to figure the calculation for. Bicycle frames are certainly flexy flexy flexy, but hey all bikes flex. Some in different ways than others. Some are stout, some are not.. but they all flex.
I would need 40s. 40s, on my motor. 144v, nominal. 168v charged. This would put me right at 100mph loaded, in theory. 40 cells is alot to put on a bike. Every cell I add would add 2.5mph to the top end speed. I mean, I have the cells, sitting here, that would output this power.. but... they wont all fit on my bike. Nooope.
( ok maybe they would, fit... but it would be bulky and no longer "look " like a bicycle, nosiree. )
The QS 205 V3 is said to saturate at ~32kW. I would need 400A+, I think, to get near this, gross power.
Damn vicious motor. By all definition. FoSHo.
Most I got on hand is 132v Lyen ( 7 kW?). Lots of 10, 14, even 20kW controllers out there, but not a 30kW + controller that i know of readily. Adapto, Nuclear, BAC, ect. Maybe a Kelly KHB. Or a Sevcon, maybe, but who puts a Sevcon on a hub motor.