https://medicalxpress.com/news/2017-07-bacteria-alzheimer-brains.html
What is this P. Acnes?
https://en.wikipedia.org/wiki/Propionibacterium_acnes
This is interesting, raises questions as to primary routes of entrance and exacerbating factors.
It likely enter through the skin or through the digestive tract. As to exacerbating factors, eating whatever may grow P. Acnes populations might contribute, eating whatever that opens the interstitial gaps in the body upto bacterial invasion /might/ contribute (Gliadin), then there may be issues with maintaining healthy bacterial populations on the skin (Keeping clean) if that's a viable route. The immune system may be a strong contributing factor, and a collection of items that boost it vs those items that harm it, may affect alzheimers risk. For example, there might be an association between depression (immune system impairer) and alzheimers. There's likely an association between lack of sun exposure and alzheimers. There's likely a strong link between lack of frequent physical activity and alzheimers.
https://newoldage.blogs.nytimes.com/2013/05/01/does-depression-contribute-to-dementia/
For sure, this does suggest an association between acne and alzheimers.
https://www.livescience.com/8718-rare-acne-linked-alzheimer.html
Have acne inversa -> No alzheimers. What is acne inversa?
https://en.wikipedia.org/wiki/Hidradenitis_suppurativa
Interesting; on that note, acne inversa has significant comorbities so it is by no means a "good disease" to have.
I don't really understand the connection and association with p. acne and alzheimers.
They found that the Alzheimer's brains contained different proportions of specific bacteria compared with the healthy brains. "Comparing the bacterial populations showed at least a tenfold higher ratio overall of Actinobacteria (mostly P. acnes) to Proteobacteria in the Alzheimer's brain compared with the healthy brain," says Emery.
What is this P. Acnes?
https://en.wikipedia.org/wiki/Propionibacterium_acnes
Propionibacterium acnes is the relatively slow-growing, typically aerotolerant anaerobic, Gram-positive bacterium (rod) linked to the skin condition of acne;[2] it can also cause chronic blepharitis and endophthalmitis,[3] the latter particularly following intraocular surgery. The genome of the bacterium has been sequenced and a study has shown several genes can generate enzymes for degrading skin and proteins that may be immunogenic (activating the immune system).[4]
This bacterium is largely commensal and part of the skin flora present on most healthy adult humans' skin.[5] It is usually just barely detectable on the skin of healthy preadolescents. It lives primarily on, among other things, fatty acids in sebum secreted by sebaceous glands in the follicles. It may also be found throughout the gastrointestinal tract in humans[6] and many other animals.
This is interesting, raises questions as to primary routes of entrance and exacerbating factors.
It likely enter through the skin or through the digestive tract. As to exacerbating factors, eating whatever may grow P. Acnes populations might contribute, eating whatever that opens the interstitial gaps in the body upto bacterial invasion /might/ contribute (Gliadin), then there may be issues with maintaining healthy bacterial populations on the skin (Keeping clean) if that's a viable route. The immune system may be a strong contributing factor, and a collection of items that boost it vs those items that harm it, may affect alzheimers risk. For example, there might be an association between depression (immune system impairer) and alzheimers. There's likely an association between lack of sun exposure and alzheimers. There's likely a strong link between lack of frequent physical activity and alzheimers.
https://newoldage.blogs.nytimes.com/2013/05/01/does-depression-contribute-to-dementia/
The researchers found that depressed older adults (defined as those over age 50) were more than twice as likely to develop vascular dementia and 65 percent more likely to develop Alzheimer’s disease than similarly aged people who weren’t depressed.
For sure, this does suggest an association between acne and alzheimers.
https://www.livescience.com/8718-rare-acne-linked-alzheimer.html
Though both Alzheimer's and acne inversa appear to be caused by mutations in PSEN1, there have not been any reported cases of both diseases occurring together, the researchers said. None of the fifty subjects in the new study exhibited symptoms of Alzheimer's disease or dementia.
Have acne inversa -> No alzheimers. What is acne inversa?
https://en.wikipedia.org/wiki/Hidradenitis_suppurativa
Interesting; on that note, acne inversa has significant comorbities so it is by no means a "good disease" to have.
I don't really understand the connection and association with p. acne and alzheimers.